Displaying posts tagged with

“immune system”

Studies and research made on PSP | Yunzhi-PSP

In terms of the survival time of mice in oxygen-lacking conditions, PSP test group has a much higher ability of anoxia tolerance.[…]

CIMER – Coriolus versicolor (mushroom) – MD Anderson Cancer Center Page 1

The anti-cancer and immune stimulating properties of Coriolus versicolor have been attributed to two extracts from its cultured mycelium (thread-like extensions). These extracts are both protein-bound polysaccharides known as polysaccharide K (PSK) and polysaccharide-peptide (PSP). Hot water is required to extract these active components. {…}

The Main Functions of Yun Zhi

Yun Zhi, commonly known as coriolus versicolor, is a wonderful remedy for health and healing. Yun Zhi’s shelf-like fruiting bodies form dense, overlapping clusters on tree trunks. The mushroom caps have plush velvety surfaces and are coloured in varying shades of brown or gray, with a distinctive alternating-band pattern of light and dark colours. Many international journals support the positive effects of Yun Zhi on health. Nowadays, many medical and nutritional studies find that the key active ingredient of Yun Zhi, polysaccharides, has greatly contribute to, relieving pain, improve immune functions, reduced anti- asphyxia, and enhance cell regeneration. According to experiments, polysaccharides can also help promote anti-tumors without negative side effects.[…]

Antimetastatic Effects of PSK (Krestin), a Protein-bound Polysaccharide Obtained from Basidiomycetes: An Overview

PSK is currently used as an immuno therapeutic agent for gastric colorectal, and lung cancers in Japan. It has virtually no adverse effects, and it can be administered P. over a long term. Consequently, its use need not be limited to the treatment of Cancer, and, as our previous paper suggested, it should in the future prove valuable as a general chemopreventive agent and, as this review shows, as anti metastatic agent. The principal mechanisms of PSK may act as an inhibitor of the motility, invasion, and progression of tumor cells, in addition to its role as an immunomodulator.[…]

The culture duration affects the immunomodulatory and anticancer effect of polysaccharopeptide derived from Coriolus versicolor

Flow cytometry analysis on cell cycle and cell death (apoptosis) of Molt 4 cells indicated that the anticancer mechanism of PSP is related to its ability to induce S-phase cell arrest and apoptosis, respectively. Together, these results suggest that monitor the harvest duration is critical for the quality control of polysaccharopeptide in the biotechnological industry.[…]

How inForce immune builder rebuilt ones immunes system that was compromised by the West Nile Virus.

I recently discovered in March 2010 that I had a very high C – reactive protein level of 20.4. The normal range for this level is below 3. I was diagnosed in July 2004 with having been exposed to the West Nile Virus and I knew I had been sick allot and running a elevated temperature for months visiting the urgent care department every 6 weeks and taking antibiotics. I would no more be off the antibiotics for a week to 10 days and I was right back to seeing the doctors at urgent care. The doctors had put me through a series of test and scans to determine the point of origin of the inflammation, with no success….

Induction of cell cycle changes and modulation of apoptogenic/anti-apoptotic and extracellular signaling regulatory protein expression by water extracts of I’m-Yunity™ (PSP)

Aqueous extracts of I’m-Yunity™ (PSP) induces cell cycle arrest and alterations in the
expression of apoptogenic/anti-apoptotic and extracellular signaling regulatory proteins in human leukemia
cells, the net result being suppression of proliferation and increase in apoptosis. These findings may
contribute to the reported clinical and overall health effects of I’m-Yunity™ (PSP). […]

[Effect of ATSO from Coriolus versicolor on immune response (author’s transl)]

[Effect of ATSO from Coriolus versicolor on immune response (author’s transl)][…]

Krestin (PSK).

A polysaccharide preparation isolated from Coriolus versicolor (Fr.) Quél. of Basidiomycetes (PSK) predominantly consists of glucan and approximately 25% tightly bound protein. PSK was effective against various allogeneic and syngeneic animal tumors and has been given orally to cancer patients. Various suppressed or enhanced immune responses of tumor-bearing animals were restored to normal levels by the administration of PSK in the tumor models tested. The killer T cell activity was augmented in tumor-bearing mice by intraperitoneal or oral administration of PSK, and there was correlation between the PSK associated antitumor effect and the killer T cell activity. It was found that PSK competed with immunosuppressive substances isolated from tumor-bearing mice and that the intestinal immune system appeared to be modulated by oral administration of PSK. After oral administration of 14C- or 35S-labeled PSK to normal rats, it was found that small or large molecular substances appeared in the serum depending on the time elapsed after administration, an indication that large molecular size products were from the digestive tract.[…]

Effects of Coriolus versicolor polysaccharides peptides on electric activity of mediobasal hypothalamus and on immune function in rats.

MBH is involved in the immune-potentiating effect of PSP.[…]