Displaying posts tagged with

“clinical trial”

Research Papers by Year and Research Institutes | Yunzhi-PSP

Comparsion of Anti-cancer Effect between two kinds of Polysaccharide Peptide of Coriolus versicolor on Human Tumor Cell Lines in Vitro{…}

CORIOLUS MUSHROOM: Uses, Side Effects, Interactions and Warnings – WebMD

Cancer when used with chemotherapy. Taking polysaccharide krestin (PSK), a substance found in coriolus mushroom, may improve some cancer patients’ response to chemotherapy. PSK has been used in Japan for several decades for breast cancer, esophageal cancer, gastric cancer, lung cancer, hepatic cancer, colorectal cancer, and nasopharyngeal cancer. Results have varied.

Clinical Trial China phase 3

Based on the PSP´s significant findings in the investigated cancers of the Phase II trial, permission was granted by the Chinese Administration of Health Bureau to carry out a multi-center Phase III clinical trial. Fourteen hospitals including the eight who participated in the phase II trial conducted this randomized study from April 1996 to September 1997.[…]

Clinical trial China phase 2

Polysaccharide-peptide (PSP) is a protein bound polysaccharide isolated from the COV-1 strain of Yunzhi (Coriolous versicolor mushroom) and made from modern alcohol extraction techniques. Each capsule contains 0.34 grams of PSP. Experimental in-vitro and in-vivo studies have shown PSP inhibits the proliferation of cancer cells including P338 leukemia cells, S 180 cells, Ehrlich ascites, and stomach and lung cancer cells. It also inhibits the growth of some tumors such as the lymphatic tumor of human skin tissue cells. In addition, PSP affects the immune system of mice by stimulating the production of ?\interferons, increasing the phagocytic index and metabolic rate of the reticuloendothilial system and by raising the HC 50 (median hemolytic dose), IgG and PFC (plaque forming cell) values. Human in-vivo experiments have also shown PSP can modulate the immune system by helping to prevent and partly eliminate the side effects of radiation and chemotherapeutic agents used by cancer patients. […]

Add mushrooms to list of cancer treatment tools – By: Dr. Patrick Massey, M.D., Ph.D., Daily Herald Columnist

(Daily Herald – 9/8/2008) When it comes to cancer treatment, I believe that we have finally reached a point where we need to seriously consider incorporating mushrooms into the overall medical approach.

A review article outlining the importance of one specific mushroom – Coriolus versicolor – in the treatment of several types of cancer was published in the recent issue of the Journal of the Society for Integrative Oncology. The article summarizes more than three decades of solid research that showed patients who consumed Coriolus versicolor or one of its extracts during chemotherapy had better survival rates. […]

Clinical Trial Results Show Proof-of-Concept For Use Of Coriolus Versicolor As Immunonutrition In HPV Patients With Cervical Lesions (LSIL)

(Medical News Today – 4/29/2008) Result: Of the 39 patients who completed one year of follow-up, 18 took Coriolus supplementation, while the other 21 patients received no therapy (Control group). After 1 year 13 of the 18 patients in the Coriolus group showed normal cervical cytology (72.5%) while only 10 of the patients in the control group did (47.5%).

Of the 39 patients, 22 were positive for high risk HPV subtypes.10 of these patients were in the Coriolus group and 12 in the control group. After 1 year 9 of the 10 in the Coriolus group had reverted to HPV- status (90%) while only 1 of the 12 in the control group had (8.5%). […]

Adjuvant PSK immunotherapy in patients with carcinoma of the nasopharynx.

A controlled study using adjuvant PSK immunotherapy in patients with nasopharyngeal carcinoma was initiated with the aim of improving survival by enhancing the host immune system against tumour cells. A total of 38 patients were randomly selected, all of whom had previously received radiotherapy with or without chemotherapy. Eight patients in the PSK immunotherapy group (n = 21) developed […]

Hartford Hospital, Conneticut & Coriolus Vericolor PSK/PSP

What Hartford Hospital in Conneticut has to say about Coriolus Versicolor “Currently, extracts of Coriolus versicolor called polysaccharide-K (PSK) and polysaccharopeptide (PSP) are under study as immune stimulants for use alongside chemotherapy in the treatment of cancer. These two related substances, made from slightly different strains of the fungus, are thought to act as “biological […]