Displaying posts tagged with

“autoimmune”

A Life long battle with arthritis, fibro, auto-immune disease, and scoliosis. A brighter future with inForce™ Immune Builder with PSK

I was born with Scoliosis, Pediatric Fibromyalgia and a weakened auto-immune system. What that means is from infancy, until the age of 11 years old, I woke up in the morning to start my day, unable to open my eyes.

They were glued shut from an excess accumulation of mucus overnight, which would harden and interlock my eye-lashes thus, by dawn my eyes were sealed shut. My mother’s daily routine was to place hot, wet towels over my eyes to loosen the mucus and remove it without removing my eye-lashes as well. Once that was done and I could open my eyes to see, my mother would drive me to my doctors office, where I would have to sit at a machine, equivalent to a vacuum cleaner sucking excess mucus from each nostril. It was a painful, childhood experience which I will never forget….

Polysaccharopeptide mimics ciclosporin-mediated Th1/Th2 cytokine balance for suppression of activated human T cell proliferation by MAPKp38 and STAT5 pathways.

The data show that PSP alone suppresses the proliferation of activated T cells. PSP exhibited similar and additive inhibitory effects to ciclosporin to suppress activated T cell proliferation, Th1 cytokines and reduce CD3+/CD25+ cell expression, but not Th2 cytokine expression, which helps the cytokine balance shift towards Th2 dominance. These suppressive actions of PSP involved the MAPKp38 and STAT5 pathways. These findings refine our understanding of the effects of PSP on T lymphocytes and its adjuvant properties with the immunosuppressant ciclosporin for possible control of autoimmune diseases.[…]