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June 2011

Immunomodulating Actions of PSP

PsP, the protein-bound polysaccharide, extracted from a strain of Coriolus versicolor (Cov-1) by Professor Qing-yao Yang, has been proved to be effective against tumor both in animal experiments and in clinical patients. Previous results suggested that the antitumor effects of PsP were related to the potentiation of immunological responses, especially T-cell mediated immune responses of tumorbearing hosts. Since T-lymphocytes play an important role in immune response and T-cell deficiency existed in many diseases, the most noticeable one at present time is the acquired immune deficient syndrome (AIDS) which leads to the failure of T-cell functions and death. Until now there is no any
effective drug in curing this disease. It is of great interest to investigate if PsP can potentiate T-cell functions and restore the immune deficient conditions in tumor, AIDS and other viral infections. In this paper both in vivo and in vitro experiments were used to study PsP on: 1) immune organ weights, 2) antibody informations, 3) serum complement contents, 4) T lymphocyte proliferations, 5) interleukin-2 production, 6) delayed type hypersensitivity reaction, 7) phagocytic ability of reticulo-endothelial system and 8) protection of liver injuries from CCl4 intoxication.[…]

PSP, Coriolus Polysaccharide: Intra-Cellular Mycelia Extract of Coriolus Versicolor

As the leader in standardized mushroom extracts we believe passionately in sharing information from the growing body of published research on medicinal mushrooms. This is for education purposes only and MYCOPHARMA® cannot and does not vouch for the accuracy of independent research. To make your own informed decisions please refer to the original published research about Coriolus Versicolor.{…}

Research Papers by Year and Research Institutes | Yunzhi-PSP

Comparsion of Anti-cancer Effect between two kinds of Polysaccharide Peptide of Coriolus versicolor on Human Tumor Cell Lines in Vitro{…}

Studies and research made on PSP | Yunzhi-PSP

In terms of the survival time of mice in oxygen-lacking conditions, PSP test group has a much higher ability of anoxia tolerance.[…]

The Preliminary Appraisal of Polysaccharide Peptide (PSP) in Malignant and Non-malignant Diseases

So far no adverse drug reaction has been observed, there were no impairment of liver and renal functions after the long term administration of PSP even up to years.[…]

Trametes versicolor – Wikipedia, the free encyclopedia

Trametes versicolor — formerly known as Coriolus versicolor and Polyporus versicolor — is an extremely common polypore mushroom which can be found throughout the world. Versicolor means ‘of several colours’ and it is true that this mushroom is found in a wide variety of different colours. T. versicolor is commonly called Turkey Tail in the United States because of its resemblance to the tail of the wild turkey. T. versicolor is recognized as a medicinal mushroom in Chinese medicine under the name yun zhi (simplified Chinese: ??, traditional Chinese: ? ?). In China and Japan T. versicolor is used as in immunoadjuvant therapy for cancer.[…]

CIMER – Coriolus versicolor (mushroom) – MD Anderson Cancer Center Page 1

The anti-cancer and immune stimulating properties of Coriolus versicolor have been attributed to two extracts from its cultured mycelium (thread-like extensions). These extracts are both protein-bound polysaccharides known as polysaccharide K (PSK) and polysaccharide-peptide (PSP). Hot water is required to extract these active components. {…}