U.S. National Library of Medicine
National Institutes of Health
In Vivo. 1994 Mar-Apr;8(2):247-50.
Kanoh T, Matsunaga K, Saito K, Fujii T.
Kureha Chemical Ind. Co., Ltd., Biomedical Research Laboratories, Tokyo, Japan.
The anti-angiogenic effects of an antitumor protein-bound polysaccharide, PSK, obtained from cultured mycelia of Coriolus
versicolor in basidiomycetes were examined by the mouse dorsal air sac assay. PSK suppressed the mouse hepatoma
MH134-induced angiogenesis when assessed by morphological and biochemical examinations. This finding suggested that
the anti-metastatic effect of PSK is attributed to the suppression of tumor-induced angiogenesis.
PMID: 7522606 [PubMed – indexed for MEDLINE]