An effect of adjuvant immunochemotherapy using krestin and 5-FU on gastric cancer patients with radical surgery (first report)–a randomized controlled trial by the cooperative study group. Study Group of Immuno-chemotherapy with PSK for Gastric Cancer

To evaluate the efficacy of PSK for adjuvant immuno-chemotherapy in patients who had undergone radical gastrectomy, a randomized controlled trial has been in progress in collaboration with 46 institutions in the Chubu district of Japan. A total of 262 patients were registered for this trial during the two years from July 1985 to June 1987 with a centralized registration system, and were allocated into the 5-FU+PSK group (Group P) and 5-FU alone group (Group C) by the minimization method following the random permuted blocks method. Between the two groups, the parameters of sex, age, serosal invasion (S), lymph-node metastasis (N), and the combination of S . N factor levels were distributed without significant differences. An induction treatment with MMC 6 mg/m2 was given to all patients following curative mastectomy and on the 7th post-operative day. Two weeks after surgery, Group P received alternately PSK 3 g/day for 4 week and 5-FU 150 mg/day for 4 weeks as one course, and 10 courses were given. Group C received 5-FU alone for 4 weeks using alternate rest interval for 4 weeks. Since both experimental and clinical studies suggested that alternate treatments using PSK and anticancer agents were effective, treatment in this trial alternated PSK and 5-FU. A final follow-up study will be completed in June 1992, when all patients shall have survived more than 5 years after surgery. The administration of 5-FU was completed by January. 1989, but PSK has been administered to group P. The period from 18 to 42 months after surgery was reached in all eligible patients (253) at the end of December 1988. The disease-free survival curves and overall survival curves of group P were significantly (p = 0.018 and p = 0.045,) better than those of group C.

2 Responses to “An effect of adjuvant immunochemotherapy using krestin and 5-FU on gastric cancer patients with radical surgery (first report)–a randomized controlled trial by the cooperative study group. Study Group of Immuno-chemotherapy with PSK for Gastric Cancer”

  1. Anita Hall says:

    I have a few questions about your mushrooms. My childrens Grandparents were both told they have bone cancer. The women was told she was in stage four bone cancer, she started out with breast cancer. Her husband was just told In Sept of this year he has bone cancer also. My husband has prostate cancer and has to have surgery in the near future. I want to know if these mushrooms will help any of them? The women is in alot of pain with her cancer, is she to far for the mushrooms to help her?? She does have good days and bad days. Will it do any good for the prostate cancer, which the cancer is only in the prostate, has not spread yet?? Please get back with me asap so we can get started on this program. I would like to know how often each person would have to take these also, and how much to day any good.
    Thank you, and I will be waiting for a response from you.
    Anita Hall

    • admin says:

      Anita,
      Coriolus versicolor does not cure anything directly. It is a dietary supplement and it simply modulates or helps one’s own immune system. Once a person has good working immune system, then he/she can war off many illnesses.

      We have seen many awesome testimonials with Coriolus versicolor building people’s own immune system back to working order. Of course, each person’s case is different but many people have seen results in less than a month.

      When it comes to usage, all research points to at least 3 grams per day but testimonials show many people taking 6 grams per day.

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